Times of Israel piece, March 2022

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Loss of heterochromatin and retrotransposon silencing as determinants in oocyte aging

Wasserzug-Pash et al., Aging Cell 2022


Endurance of extremely prolonged nutrient prevention across kingdoms of life

Hazan Schoemann and Klutstein, iScience 2021


Age-Dependent in vitro Maturation Efficacy of Human Oocytes - Is There an Optimal Age?

Karavani et al. Front Cell Dev Biol 2021

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A Mouse Model for Studying the Development of Apical Periodontitis with Age
Goldman et al.  MDPI Cells 2021


Ynet article on the Nature paper


Centromeres are dismantled by foundational meiotic proteins Spo11 and Rec8

Hou et al. Nature 2021


Cause and effect in epigenetics - where lies the truth, and how can experiments reveal it?: Epigenetic self-reinforcing loops obscure causation in cancer and aging

Klutstein Bioessays 2021

Colon Cancer-Associated Fusobacterium nucleatum May Originate From the Oral Cavity and Reach Colon Tumors via the Circulatory System

Abed et al. Front Cell Infect Microbiol 2020

Since 2013, Björn Schumacher is full professor and director of the Institute for Genome Stability in Ageing and Diseases (IGSAD) at the CECAD Research Centre of the University of Cologne. He received his PhD at the Max Planck Institute for Biochemistry in Munich and conducted his postdoctoral research as EMBO and Marie Curie fellow at the Erasmus Medical Centre in Rotterdam. B.S. was awarded with the Eva Luise Köhler Research Prize, the Innovation Prize of the State of North Rhine-Westphalia, the European Research Council (ERC) starting grant, and coordinated the FP7 Marie Curie initial training network on chronic DNA damage in ageing (CodeAge). Professor Schumacher served as President of the German Society for Ageing Research (DGfA) and is currently Vice President of the German Society for DNA Repair (DGDR), co-Director of the Minerva Center of the Biological Mechanisms of Healthy Ageing at Bar-Ilan University (IL) and serves on several editorial boards. His research interest focuses on the molecular mechanisms through which DNA damage contributes to cancer development and ageing-associated diseases. Employing the C. elegans system and mammalian disease models, his group uncovered cell-autonomous and systemic responses through which the organism adapts to accumulating DNA damage with ageing. Through the understanding of the basic mechanisms of genome instability-driven ageing, Schumacher aims to contribute to the development of future strategies to prevent ageing-associated diseases.

Isolation and Characterization of Live Yeast Cells from Ancient Clay Vessels

Aouizerat et al. Bio-Protocol 2020

BBC on the ancient beer

Eukaryotic Adaptation to Years-Long Starvation Resembles that of Bacteria

Aouizerat et al. iScience 2019

Inducing Apical Periodontitis in Mice

Goldman et al. JoVE 2019

Isolation and Characterization of Live Yeast Cells from Ancient Vessels as a Tool in Bio-Archaeology

Aouizerat et al. mBio 2019

Epigenetic changes in mammalian gametes throughout their lifetime: the four seasons metaphor

Wasserzug-Pash and Klutstein, Chromosoma, 2019


YNET article on the lab

Contribution of epigenetic mechanisms to variation in cancer risk among tissues

Klutstein M, Moss J, Kaplan T, Cedar H PNAS 2017


DNA Methylation in Cancer and Aging

Klutstein M, Nejman D, Greenfield R, Cedar H Cancer Research 2016

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